Micronization of Cetirizine Using Rapid Expansion of Supercritical Carbon Dioxide

Micronization of Poorly Water-Soluble Trichlorocarbanilide Using Supercritical Carbon Dioxide

Trichlorocarbanilide has widely been used in cosmetics and household products, but the extremely low solubility of trichlorocarbanilide in water constrains the development of water-based products. In order to enhance the bioavailability, trichlorocarbanilide were micronized using supercritical fluid. Supercritical carbon dioxide was selected due to relatively low critical temperature and the ra...

The characteristics of coherent structures in the rapid expansion flow of the supercritical carbon dioxide

By the use of a tiny pressure-transferring probe and capacitor-type sensor, the dynamic pressure signals in the jet flow of the rapid expansion of supercritical carbon dioxide are measured, which distinctively shows the characteristics of quasi-periodical coherent structures. After Fast Fourier Transform (FFT) conversion of the time series signals of the dynamic pressure, there exist three domi...

Micronization of magnolia bark extract with enhanced dissolution behavior by rapid expansion of supercritical solution.

A rapid expansion of supercritical solution (RESS) technology was presented for the micronization of Chinese medicinal material. Magnolia bark extract (MBE) obtained by supercritical carbon dioxide (scCO(2)) extraction technology was chosen as the experimental material. RESS process produced 4.7 microm size MBE microparticles (size distribution, 0.2-24.1 microm), which was significantly smaller...

Vetiver Oil Extraction Optimization Using Supercritical Carbon Dioxide Fluid

Measurement and Modeling of Acridine Solubility in Supercritical Carbon Dioxide

Supercritical carbon dioxide has gained increasing attention in food and pharmaceutical processing owing to the fact that it is environmentally inexpensive, not flammable, essentially non-toxic, and it has a convenient critical point. Also, it has been attracting much attention in many fields, such as extraction of sensitive materials and pharmaceutical processing and polymerization processes. ...